Gene description for SPN
Gene name	sialophorin
Gene symbol	SPN
Other names/aliases	CD43 GALGP GPL115 LSN
Species	Homo sapiens
Database cross references - SPN
ExoCarta	ExoCarta_6693
Vesiclepedia	VP_6693
Entrez Gene	6693
HGNC	11249
MIM	182160
UniProt	P16150
SPN identified in exosomes derived from the following tissue/cell type
B cells	20458337
B cells	20458337
B cells	20458337
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026

Gene ontology annotations for SPN

Molecular Function     protein binding GO:0005515 IPI     transmembrane signaling receptor activity GO:0004888 TAS Biological Process     chemotaxis GO:0006935 TAS     response to protozoan GO:0001562 IEA     negative regulation of type IV hypersensitivity GO:0001808 IEA     signal transduction GO:0007165 TAS     negative regulation of T cell proliferation GO:0042130 IEA     T cell costimulation GO:0031295 IEA     defense response to bacterium GO:0042742 IDA     regulation of defense response to virus GO:0050688 IEA     apoptotic signaling pathway GO:0097190 IEA     positive regulation of protein phosphorylation GO:0001934 IEA     positive regulation of T cell proliferation GO:0042102 IEA     cellular defense response GO:0006968 TAS     establishment or maintenance of cell polarity GO:0007163 TAS     immune response GO:0006955 TAS     negative thymic T cell selection GO:0045060 IEA     negative regulation of cell adhesion GO:0007162 TAS     cell surface receptor signaling pathway GO:0007166 IEA     blood coagulation GO:0007596 TAS     positive regulation of tumor necrosis factor biosynthetic process GO:0042535 IDA     leukocyte migration GO:0050900 TAS Subcellular Localization     extracellular space GO:0005615 IDA     membrane GO:0016020 IDA     plasma membrane GO:0005886 TAS     integral component of plasma membrane GO:0005887 IEA     cell surface GO:0009986 IDA     extracellular exosome GO:0070062 IDA     uropod GO:0001931 IEA     external side of plasma membrane GO:0009897 IEA     basement membrane GO:0005604 IEA