Gene description for NCAPG2
Gene name non-SMC condensin II complex, subunit G2
Gene symbol NCAPG2
Other names/aliases CAP-G2
CAPG2
LUZP5
MTB
hCAP-G2
Species Homo sapiens
 Database cross references - NCAPG2
ExoCarta ExoCarta_54892
Entrez Gene 54892
HGNC 21904
MIM 608532
UniProt Q86XI2  
 NCAPG2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for NCAPG2
Molecular Function
    protein binding GO:0005515 IPI
    methylated histone binding GO:0035064 IDA
Biological Process
    mitotic cell cycle GO:0000278 TAS
    mitotic nuclear division GO:0007067 IEA
    chromosome condensation GO:0030261 IEA
    cell division GO:0051301 IEA
    inner cell mass cell proliferation GO:0001833 IEA
Subcellular Localization
    nucleoplasm GO:0005654 TAS
    membrane GO:0016020 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified NCAPG2 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NCAPG2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TAL1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which NCAPG2 is involved
PathwayEvidenceSource
Condensation of Prophase Chromosomes TAS Reactome





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