Gene description for KALRN
Gene name	kalirin, RhoGEF kinase
Gene symbol	KALRN
Other names/aliases	ARHGEF24 CHD5 CHDS5 DUET DUO HAPIP TRAD
Species	Homo sapiens
Database cross references - KALRN
ExoCarta	ExoCarta_8997
Entrez Gene	8997
HGNC	4814
MIM	604605
UniProt	O60229
KALRN identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113
Urine	19056867

Gene ontology annotations for KALRN

Molecular Function     metal ion binding GO:0046872 IEA     Rho guanyl-nucleotide exchange factor activity GO:0005089 IEA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     guanyl-nucleotide exchange factor activity GO:0005085 EXP     protein serine/threonine kinase activity GO:0004674 IEA Biological Process     vesicle-mediated transport GO:0016192 TAS     positive regulation of GTPase activity GO:0043547 TAS     regulation of small GTPase mediated signal transduction GO:0051056 TAS     intracellular signal transduction GO:0035556 ISS     axon guidance GO:0007411 TAS     small GTPase mediated signal transduction GO:0007264 TAS     apoptotic signaling pathway GO:0097190 TAS     positive regulation of apoptotic process GO:0043065 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     ephrin receptor signaling pathway GO:0048013 TAS     signal transduction GO:0007165 TAS     nervous system development GO:0007399 ISS     protein phosphorylation GO:0006468 IEA Subcellular Localization     actin cytoskeleton GO:0015629 TAS     extracellular exosome GO:0070062 IDA     cytosol GO:0005829 TAS