Gene description for RREB1 |
Gene name |
ras responsive element binding protein 1 |
Gene symbol |
RREB1 |
Other names/aliases |
FINB HNT LZ321 RREB-1 Zep-1 |
Species |
Homo sapiens |
Database cross references - RREB1 |
ExoCarta |
ExoCarta_6239 |
Entrez Gene |
6239 |
HGNC |
10449 |
MIM |
602209 |
UniProt |
Q92766
|
RREB1 identified in exosomes derived from the following tissue/cell type |
Neuroblastoma cells
|
25944692
|
Urine
|
19056867
|
Gene ontology annotations for RREB1 |
|
Experiment description of studies that identified RREB1 in exosomes |
1 |
Experiment ID |
224 |
ISEV standards |
✔
EM|AFM
|
EV Biophysical techniques |
✔
Alix|TSG101
|
EV Cytosolic markers |
✔
CD63|CD81
|
EV Membrane markers |
✔
GOLGA2
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25944692
|
Organism |
Homo sapiens |
Experiment description |
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes |
Authors |
Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S |
Journal name |
Oncotarget
|
Publication year |
2015 |
Sample |
Neuroblastoma cells |
Sample name |
SH-SY5Y |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density |
1.10 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry Western blotting |
|
|
2 |
Experiment ID |
63 |
ISEV standards |
✘
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✔
AQP2
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
19056867
|
Organism |
Homo sapiens |
Experiment description |
Large-scale proteomics and phosphoproteomics of urinary exosomes. |
Authors |
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA |
Journal name |
JASN
|
Publication year |
2009 |
Sample |
Urine |
Sample name |
Urine - Normal |
Isolation/purification methods |
Differential centrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [LTQ] Western blotting |
|
|
Protein-protein interactions for RREB1 |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which RREB1 is involved |
No pathways found
|
|
|