Gene description for LYPLAL1
Gene name lysophospholipase-like 1
Gene symbol LYPLAL1
Other names/aliases Q96AV0
Species Homo sapiens
 Database cross references - LYPLAL1
ExoCarta ExoCarta_127018
Entrez Gene 127018
HGNC 20440
UniProt Q5VWZ2  
 LYPLAL1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for LYPLAL1
Molecular Function
    lysophospholipase activity GO:0004622 NAS
Biological Process
    negative regulation of Golgi to plasma membrane protein transport GO:0042997 IEA
    biological_process GO:0008150 ND
    protein depalmitoylation GO:0002084 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IEA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified LYPLAL1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LYPLAL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LYPLAL1 is involved
No pathways found





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