Gene description for SUMF2
Gene name sulfatase modifying factor 2
Gene symbol SUMF2
Other names/aliases pFGE
Species Homo sapiens
 Database cross references - SUMF2
ExoCarta ExoCarta_25870
Vesiclepedia VP_25870
Entrez Gene 25870
HGNC 20415
MIM 607940
UniProt Q8NBJ7  
 SUMF2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for SUMF2
Molecular Function
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
    metal ion binding GO:0046872 IEA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum lumen GO:0005788 TAS
 Experiment description of studies that identified SUMF2 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SUMF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 COA4  
Co-fractionation Homo sapiens
2 AK4 205
Co-fractionation Homo sapiens
3 TUBA1A 7846
Affinity Capture-MS Homo sapiens
4 WDR34 89891
Affinity Capture-MS Homo sapiens
5 CACNA1A  
Two-hybrid Homo sapiens
6 ZFYVE9  
Two-hybrid Homo sapiens
7 AK2 204
Co-fractionation Homo sapiens
8 SOD1 6647
Co-fractionation Homo sapiens
9 CANX 821
Affinity Capture-MS Homo sapiens
10 MSRB2  
Co-fractionation Homo sapiens
11 LRRC59 55379
Proximity Label-MS Homo sapiens
12 PDIA4 9601
Proximity Label-MS Homo sapiens
13 CALU 813
Proximity Label-MS Homo sapiens
14 CALR3  
Proximity Label-MS Homo sapiens
15 ZDHHC17 23390
Two-hybrid Homo sapiens
16 GRHPR 9380
Co-fractionation Homo sapiens
17 PLD4  
Affinity Capture-MS Homo sapiens
18 ANKRD40 91369
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 LYPLAL1 127018
Co-fractionation Homo sapiens
20 FAHD1 81889
Co-fractionation Homo sapiens
21 CCT6B 10693
Affinity Capture-MS Homo sapiens
22 TXNDC12 51060
Co-fractionation Homo sapiens
23 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
24 APOD 347
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 APEX1 328
Affinity Capture-RNA Homo sapiens
26 EFNA3  
Affinity Capture-MS Homo sapiens
27 TXN2 25828
Co-fractionation Homo sapiens
28 E2F4  
Affinity Capture-MS Homo sapiens
29 B3GNT2 10678
Affinity Capture-MS Homo sapiens
30 ABHD11 83451
Co-fractionation Homo sapiens
31 HSPA2 3306
Affinity Capture-MS Homo sapiens
32 CLU 1191
Affinity Capture-MS Homo sapiens
33 DGUOK  
Co-fractionation Homo sapiens
34 FBXW7  
Two-hybrid Homo sapiens
35 AK3 50808
Co-fractionation Homo sapiens
36 CCT3 7203
Affinity Capture-MS Homo sapiens
37 TRIAP1  
Co-fractionation Homo sapiens
38 LYPLA1 10434
Co-fractionation Homo sapiens
39 ARSK  
Affinity Capture-MS Homo sapiens
40 AK1 203
Co-fractionation Homo sapiens
41 CKMT1B 1159
Co-fractionation Homo sapiens
42 SEC61B 10952
Proximity Label-MS Homo sapiens
43 H2AFX 3014
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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