Gene description for WASL
Gene name	Wiskott-Aldrich syndrome-like
Gene symbol	WASL
Other names/aliases	N-WASP NWASP WASPB
Species	Homo sapiens
Database cross references - WASL
ExoCarta	ExoCarta_8976
Entrez Gene	8976
HGNC	12735
MIM	605056
UniProt	O00401
WASL identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723
Neuroblastoma cells	25944692
Urine	19056867

Gene ontology annotations for WASL

Molecular Function     GTPase regulator activity GO:0030695 TAS     protein binding GO:0005515 IPI     actin binding GO:0003779 IEA Biological Process     protein complex assembly GO:0006461 TAS     small GTPase mediated signal transduction GO:0007264 TAS     Fc-gamma receptor signaling pathway involved in phagocytosis GO:0038096 TAS     innate immune response GO:0045087 TAS     transcription, DNA-templated GO:0006351 IEA     spindle localization GO:0051653 IEA     ephrin receptor signaling pathway GO:0048013 TAS     positive regulation of Arp2/3 complex-mediated actin nucleation GO:2000601 IEA     vesicle organization GO:0016050 ISS     negative regulation of membrane tubulation GO:1903526 IDA     membrane budding GO:0006900 ISS     mitotic nuclear division GO:0007067 IEA     actin polymerization or depolymerization GO:0008154 TAS     nitric oxide metabolic process GO:0046209 TAS     regulation of transcription, DNA-templated GO:0006355 IEA     cell division GO:0051301 IEA     regulation of nitric-oxide synthase activity GO:0050999 TAS     cellular protein complex localization GO:0034629 IEA     positive regulation of clathrin-mediated endocytosis GO:2000370 ISS     response to bacterium GO:0009617 IEA     regulation of protein localization GO:0032880 IEA     movement of cell or subcellular component GO:0006928 TAS     vesicle transport along actin filament GO:0030050 ISS     small molecule metabolic process GO:0044281 TAS     axon guidance GO:0007411 TAS     negative regulation of lymphocyte migration GO:2000402 IMP     positive regulation of filopodium assembly GO:0051491 ISS Subcellular Localization     lamellipodium GO:0030027 IEA     nucleus GO:0005634 IEA     actin cap GO:0030478 IEA     cytoplasmic membrane-bounded vesicle GO:0016023 ISS     plasma membrane GO:0005886 TAS     endocytic vesicle membrane GO:0030666 TAS     cytosol GO:0005829 TAS     actin cytoskeleton GO:0015629 TAS     extracellular exosome GO:0070062 IDA