Gene description for ZNF395
Gene name zinc finger protein 395
Gene symbol ZNF395
Other names/aliases HDBP-2
HDBP2
HDRF-2
PBF
PRF-1
PRF1
Si-1-8-14
Species Homo sapiens
 Database cross references - ZNF395
ExoCarta ExoCarta_55893
Entrez Gene 55893
HGNC 18737
MIM 609494
UniProt Q9H8N7  
 ZNF395 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ZNF395
Molecular Function
    DNA binding GO:0003677 IDA
    metal ion binding GO:0046872 IEA
    RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 IMP
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IC
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified ZNF395 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ZNF395
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZNF395 is involved
No pathways found





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