Gene description for CCDC51
Gene name coiled-coil domain containing 51
Gene symbol CCDC51
Other names/aliases -
Species Homo sapiens
 Database cross references - CCDC51
ExoCarta ExoCarta_79714
Vesiclepedia VP_79714
Entrez Gene 79714
HGNC 25714
UniProt Q96ER9  
 CCDC51 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for CCDC51
Molecular Function
    protein binding GO:0005515 IPI
    mitochondrial ATP-gated potassium channel activity GO:0062156 IDA
Biological Process
    cell volume homeostasis GO:0006884 IDA
    potassium ion transmembrane transport GO:0071805 IDA
    mitochondrial potassium ion transmembrane transport GO:0140141 IDA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial ATP-gated potassium channel complex GO:0062157 IDA
    mitochondrial ATP-gated potassium channel complex GO:0062157 IPI
 Experiment description of studies that identified CCDC51 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CCDC51
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HMP19  
Affinity Capture-MS Homo sapiens
2 GSX1  
Affinity Capture-MS Homo sapiens
3 FASN 2194
Positive Genetic Homo sapiens
4 NEFH 4744
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 CHCHD5  
Affinity Capture-MS Homo sapiens
6 SCIMP  
Affinity Capture-MS Homo sapiens
7 SLC25A12 8604
Proximity Label-MS Homo sapiens
8 WDFY2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 JUP 3728
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 NIN 51199
Affinity Capture-MS Homo sapiens
11 IFT20 90410
Affinity Capture-MS Homo sapiens
12 CACNG1  
Affinity Capture-MS Homo sapiens
13 IGHG1 3500
Affinity Capture-MS Homo sapiens
14 TGM3 7053
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 TPM2 7169
Affinity Capture-MS Homo sapiens
16 RPA2 6118
Proximity Label-MS Homo sapiens
17 POF1B 79983
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CDSN 1041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 DSG1 1828
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 CACNG3  
Affinity Capture-MS Homo sapiens
21 PLBD1 79887
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 TGM1 7051
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 PNMAL1  
Affinity Capture-MS Homo sapiens
24 CEACAM21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 ARG1 383
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 PKP1 5317
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 IL1R2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 NXF1 10482
Affinity Capture-RNA Homo sapiens
29 NEU2  
Affinity Capture-MS Homo sapiens
30 DUSP14 11072
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 MPL 4352
Affinity Capture-MS Homo sapiens
32 SAAL1 113174
Affinity Capture-MS Homo sapiens
33 KPRP 448834
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 IL7R  
Affinity Capture-MS Homo sapiens
35 MOV10 4343
Affinity Capture-RNA Homo sapiens
36 C10orf82  
Affinity Capture-MS Homo sapiens
37 SREBF2 6721
Positive Genetic Homo sapiens
38 C11orf87  
Affinity Capture-MS Homo sapiens
39 GM2A 2760
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 C4orf32  
Affinity Capture-MS Homo sapiens
41 COQ9  
Affinity Capture-MS Homo sapiens
42 CMTM5  
Affinity Capture-MS Homo sapiens
43 CHODL 140578
Affinity Capture-MS Homo sapiens
44 FABP5 2171
Affinity Capture-MS Homo sapiens
45 RPL35A 6165
Affinity Capture-MS Homo sapiens
46 SERPINB2 5055
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 NCCRP1 342897
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 PTPRN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 TGFA  
Affinity Capture-MS Homo sapiens
50 CPA4 51200
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 TGM5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 EVA1B 55194
Affinity Capture-MS Homo sapiens
53 KIR2DL4  
Affinity Capture-MS Homo sapiens
54 PML 5371
Affinity Capture-MS Homo sapiens
55 SNRNP27  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 AR 367
Affinity Capture-MS Homo sapiens
57 SPCS1 28972
Affinity Capture-MS Homo sapiens
58 PKP3 11187
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 SCAND1  
Two-hybrid Homo sapiens
60 ALOX12B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 PCK1 5105
Affinity Capture-MS Homo sapiens
62 ECM1 1893
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 PCDH20  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 MAEA 10296
Affinity Capture-MS Homo sapiens
65 YOD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 TMEM31  
Affinity Capture-MS Homo sapiens
67 DSP 1832
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 HYPM  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CCDC51 is involved
No pathways found





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