Gene description for CCR5
Gene name	chemokine (C-C motif) receptor 5 (gene/pseudogene)
Gene symbol	CCR5
Other names/aliases	CC-CKR-5 CCCKR5 CCR-5 CD195 CKR-5 CKR5 CMKBR5 IDDM22
Species	Homo sapiens
Database cross references - CCR5
ExoCarta	ExoCarta_1234
Vesiclepedia	VP_1234
Entrez Gene	1234
HGNC	1606
MIM	601373
UniProt	P51681
CCR5 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for CCR5

Molecular Function     virus receptor activity GO:0001618 IEA     actin binding GO:0003779 IDA     phosphatidylinositol phospholipase C activity GO:0004435 TAS     chemokine receptor activity GO:0004950 TAS     protein binding GO:0005515 IPI     coreceptor activity GO:0015026 TAS     C-C chemokine receptor activity GO:0016493 IBA     C-C chemokine receptor activity GO:0016493 IDA     C-C chemokine receptor activity GO:0016493 NAS     C-C chemokine binding GO:0019957 IPI     identical protein binding GO:0042802 IPI     chemokine (C-C motif) ligand 5 binding GO:0071791 IBA     chemokine (C-C motif) ligand 5 binding GO:0071791 IPI Biological Process     MAPK cascade GO:0000165 IEP     dendritic cell chemotaxis GO:0002407 TAS     calcium ion transport GO:0006816 IDA     apoptotic process GO:0006915 IEA     chemotaxis GO:0006935 TAS     inflammatory response GO:0006954 IBA     immune response GO:0006955 IBA     cellular defense response GO:0006968 TAS     cell surface receptor signaling pathway GO:0007166 TAS     G protein-coupled receptor signaling pathway GO:0007186 IMP     positive regulation of cytosolic calcium ion concentration GO:0007204 IBA     cell-cell signaling GO:0007267 IDA     release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 IDA     calcium-mediated signaling GO:0019722 IBA     calcium-mediated signaling GO:0019722 IDA     signaling GO:0023052 IEP     symbiont entry into host cell GO:0046718 IEA     cell chemotaxis GO:0060326 IBA     chemokine-mediated signaling pathway GO:0070098 IEA     response to cholesterol GO:0070723 IMP     cellular response to lipopolysaccharide GO:0071222 IEP     negative regulation of macrophage apoptotic process GO:2000110 IEA Subcellular Localization     cytoplasm GO:0005737 IBA     endosome GO:0005768 IDA     plasma membrane GO:0005886 TAS     external side of plasma membrane GO:0009897 IBA     external side of plasma membrane GO:0009897 IDA     cell surface GO:0009986 IDA     cell surface GO:0009986 IDA