Gene description for TRIM16
Gene name tripartite motif containing 16
Gene symbol TRIM16
Other names/aliases EBBP
Species Homo sapiens
 Database cross references - TRIM16
ExoCarta ExoCarta_10626
Entrez Gene 10626
HGNC 17241
MIM 609505
UniProt O95361  
 TRIM16 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for TRIM16
Molecular Function
    protein binding GO:0005515 IPI
    DNA binding GO:0003677 IDA
    NACHT domain binding GO:0032089 IPI
    interleukin-1 binding GO:0019966 IPI
    zinc ion binding GO:0008270 IEA
Biological Process
    positive regulation of interleukin-1 beta secretion GO:0050718 IMP
    histone H3 acetylation GO:0043966 IDA
    positive regulation of transcription, DNA-templated GO:0045893 IDA
    positive regulation of retinoic acid receptor signaling pathway GO:0048386 IDA
    response to growth hormone GO:0060416 IDA
    positive regulation of keratinocyte differentiation GO:0045618 IDA
    response to organophosphorus GO:0046683 IEP
    histone H4 acetylation GO:0043967 IDA
    response to retinoic acid GO:0032526 IEP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    PML body GO:0016605 IDA
 Experiment description of studies that identified TRIM16 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TRIM16
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TRIM16 is involved
No pathways found





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