Gene description for MRPL51
Gene name mitochondrial ribosomal protein L51
Gene symbol MRPL51
Other names/aliases CDA09
HSPC241
MRP64
bMRP64
Species Homo sapiens
 Database cross references - MRPL51
ExoCarta ExoCarta_51258
Vesiclepedia VP_51258
Entrez Gene 51258
HGNC 14044
MIM 611855
UniProt Q4U2R6  
 MRPL51 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for MRPL51
Molecular Function
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 ISS
    protein binding GO:0005515 IPI
Biological Process
    translation GO:0006412 IBA
    translation GO:0006412 ISS
    mitochondrial translation GO:0032543 ISS
    mitochondrial translation GO:0032543 NAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial ribosome GO:0005761 IDA
    mitochondrial large ribosomal subunit GO:0005762 IBA
    mitochondrial large ribosomal subunit GO:0005762 IDA
    mitochondrial large ribosomal subunit GO:0005762 ISS
    mitochondrial large ribosomal subunit GO:0005762 NAS
 Experiment description of studies that identified MRPL51 in exosomes
1
Experiment ID 236
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for MRPL51
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 H1FNT  
Affinity Capture-MS Homo sapiens
2 MRPL48  
Affinity Capture-MS Homo sapiens
3 RBMS3  
Affinity Capture-MS Homo sapiens
4 MRPL30  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 MRPL33  
Affinity Capture-MS Homo sapiens
6 RPL13A 23521
Affinity Capture-MS Homo sapiens
7 TRUB2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 NGRN  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 MRPL24  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
10 MRPL10 124995
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 MRPL27 51264
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 MRPL50 54534
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 MRPL52  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
14 RPUSD4 84881
Affinity Capture-MS Homo sapiens
15 MRPL49 740
Affinity Capture-MS Homo sapiens
16 MTRF1  
Proximity Label-MS Homo sapiens
17 MSI1  
Affinity Capture-MS Homo sapiens
18 RPS18 6222
Co-fractionation Homo sapiens
19 PSMG3 84262
Affinity Capture-MS Homo sapiens
20 MRPL20 55052
Affinity Capture-MS Homo sapiens
21 MRPL23 6150
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
22 TIMM10B 26515
Affinity Capture-MS Homo sapiens
23 YARS2  
Affinity Capture-MS Homo sapiens
24 MRPL12 6182
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 RPS9 6203
Affinity Capture-MS Homo sapiens
26 MALSU1  
Affinity Capture-MS Homo sapiens
27 LAMTOR3 8649
Co-fractionation Homo sapiens
28 MRPL39 54148
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 GNL3 26354
Affinity Capture-MS Homo sapiens
30 PMPCB 9512
Proximity Label-MS Homo sapiens
31 MRPL4 51073
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 FASTKD2  
Affinity Capture-MS Homo sapiens
33 FEM1A  
Affinity Capture-MS Homo sapiens
34 MRPL47 57129
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 FAM120A 23196
Affinity Capture-MS Homo sapiens
36 MTERF3  
Affinity Capture-MS Homo sapiens
37 MDH2 4191
Proximity Label-MS Homo sapiens
38 MRPS30 10884
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 MRPL13  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 MRPL57  
Affinity Capture-MS Homo sapiens
41 S100A2 6273
Affinity Capture-MS Homo sapiens
42 MPV17 4358
Co-fractionation Homo sapiens
43 C6orf203  
Proximity Label-MS Homo sapiens
44 MRPL17  
Affinity Capture-MS Homo sapiens
45 MRPL45 84311
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
46 RPL26 6154
Affinity Capture-MS Homo sapiens
47 TMEM177  
Co-fractionation Homo sapiens
48 ZBTB47  
Affinity Capture-MS Homo sapiens
49 SRSF3 6428
Affinity Capture-MS Homo sapiens
50 YBX2 51087
Affinity Capture-MS Homo sapiens
51 TUFM 7284
Proximity Label-MS Homo sapiens
52 MTIF3  
Proximity Label-MS Homo sapiens
53 RBMS2 5939
Affinity Capture-MS Homo sapiens
54 GFM1 85476
Proximity Label-MS Homo sapiens
55 RPL27A 6157
Affinity Capture-MS Homo sapiens
56 MRPL11 65003
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 MTRF1L  
Proximity Label-MS Homo sapiens
58 MRPL2 51069
Affinity Capture-MS Homo sapiens
59 MRPL41 64975
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 OXA1L  
Reconstituted Complex Homo sapiens
61 MRPL44  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
62 MRPL40 64976
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
63 WBSCR16  
Affinity Capture-MS Homo sapiens
64 MRPL21 219927
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
65 SRSF7 6432
Affinity Capture-MS Homo sapiens
66 MRPL35  
Affinity Capture-MS Homo sapiens
67 MRPL37 51253
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 SRSF4 6429
Affinity Capture-MS Homo sapiens
69 MRPL9 65005
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 MRPL16  
Affinity Capture-MS Homo sapiens
71 RPUSD3  
Affinity Capture-MS Homo sapiens
72 RPL3 6122
Affinity Capture-MS Homo sapiens
73 GADD45GIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 MRPL15 29088
Affinity Capture-MS Homo sapiens
75 C12orf65  
Proximity Label-MS Homo sapiens
76 MYCN  
Affinity Capture-MS Homo sapiens
77 PRR3  
Affinity Capture-MS Homo sapiens
78 TACO1  
Proximity Label-MS Homo sapiens
79 MTG1  
Proximity Label-MS Homo sapiens
80 MYC  
Affinity Capture-MS Homo sapiens
81 PTCD1 26024
Affinity Capture-MS Homo sapiens
82 MRPL3  
Affinity Capture-MS Homo sapiens
83 RPL18 6141
Affinity Capture-MS Homo sapiens
84 H2AFB2  
Affinity Capture-MS Homo sapiens
85 MRPL38  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
86 UBAC1 10422
Affinity Capture-MS Homo sapiens
87 MRPL18 29074
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 RPL19 6143
Affinity Capture-MS Homo sapiens
89 FTL 2512
Affinity Capture-MS Homo sapiens
90 RPL13 6137
Affinity Capture-MS Homo sapiens
91 YBX1 4904
Affinity Capture-MS Homo sapiens
92 RPL37 6167
Affinity Capture-MS Homo sapiens
93 MRPL42  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 TSFM 10102
Proximity Label-MS Homo sapiens
95 AUH 549
Proximity Label-MS Homo sapiens
96 PDGFB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 MRPL22  
Affinity Capture-MS Homo sapiens
98 MCAT 27349
Affinity Capture-MS Homo sapiens
99 RPL6 6128
Affinity Capture-MS Homo sapiens
100 ICT1 3396
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 FOXB1  
Affinity Capture-MS Homo sapiens
102 MRPL53  
Affinity Capture-MS Homo sapiens
103 MRPL43 84545
Affinity Capture-MS Homo sapiens
104 MRPL1  
Affinity Capture-MS Homo sapiens
105 PPP1R9B 84687
Affinity Capture-MS Homo sapiens
106 PSME3 10197
Affinity Capture-MS Homo sapiens
107 PAFAH2 5051
Affinity Capture-MS Homo sapiens
108 MAGEA9  
Affinity Capture-MS Homo sapiens
109 NUDT8  
Affinity Capture-MS Homo sapiens
110 NEIL1  
Affinity Capture-MS Homo sapiens
111 TBRG4 9238
Proximity Label-MS Homo sapiens
112 MRPL46  
Affinity Capture-MS Homo sapiens
113 MRPL19 9801
Affinity Capture-MS Homo sapiens
114 RPS8 6202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 C1QBP 708
Proximity Label-MS Homo sapiens
116 LDLR 3949
Negative Genetic Homo sapiens
117 KRAS 3845
Negative Genetic Homo sapiens
118 HNRNPU 3192
Co-fractionation Homo sapiens
119 PIPSL 266971
Affinity Capture-MS Homo sapiens
120 MRPL55  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
121 RPL36AL 6166
Affinity Capture-MS Homo sapiens
122 METTL17  
Proximity Label-MS Homo sapiens
123 MRPL28 10573
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 MRPS18A  
Affinity Capture-MS Homo sapiens
125 MRPL32 64983
Affinity Capture-MS Homo sapiens
126 RPL17 6139
Affinity Capture-MS Homo sapiens
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