Gene description for FAM111B
Gene name family with sequence similarity 111, member B
Gene symbol FAM111B
Other names/aliases CANP
POIKTMP
Species Homo sapiens
 Database cross references - FAM111B
ExoCarta ExoCarta_374393
Vesiclepedia VP_374393
Entrez Gene 374393
HGNC 24200
MIM 615584
UniProt Q6SJ93  
 FAM111B identified in sEVs derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for FAM111B
Molecular Function
    protein binding GO:0005515 IPI
    peptidase activity GO:0008233 IEA
Biological Process
    DNA replication GO:0006260 IBA
    proteolysis GO:0006508 IEA
Subcellular Localization
    chromatin GO:0000785 IBA
    nucleus GO:0005634 IBA
 Experiment description of studies that identified FAM111B in sEVs
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for FAM111B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPSA 3921
Affinity Capture-MS Homo sapiens
2 NUPL2 11097
Affinity Capture-MS Homo sapiens
3 UBE2H 7328
Affinity Capture-MS Homo sapiens
4 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
5 BAG3 9531
Affinity Capture-MS Homo sapiens
6 RPS2 6187
Affinity Capture-MS Homo sapiens
7 EXOSC9 5393
Affinity Capture-MS Homo sapiens
8 NUP155 9631
Proximity Label-MS Homo sapiens
9 ATP13A2  
Two-hybrid Homo sapiens
10 Itgb1 16412
Affinity Capture-MS Mus musculus
11 Spcs2 66624
Affinity Capture-MS Mus musculus
12 RPS19 6223
Affinity Capture-MS Homo sapiens
13 PARK2  
Affinity Capture-MS Homo sapiens
14 RPS10 6204
Affinity Capture-MS Homo sapiens
15 NXF1 10482
Affinity Capture-RNA Homo sapiens
16 MOV10 4343
Affinity Capture-RNA Homo sapiens
17 SET 6418
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
18 DTX2 113878
Proximity Label-MS Homo sapiens
19 Kctd5  
Affinity Capture-MS Mus musculus
20 Vps41  
Affinity Capture-MS Mus musculus
21 Set 56086
Affinity Capture-MS Mus musculus
22 RMDN3 55177
Proximity Label-MS Homo sapiens
23 TACC3  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FAM111B is involved
No pathways found





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