Gene description for CD8B
Gene name CD8b molecule
Gene symbol CD8B
Other names/aliases CD8B1
Species Homo sapiens
 Database cross references - CD8B
ExoCarta ExoCarta_926
Entrez Gene 926
HGNC 1707
MIM 186730
UniProt P10966  
 CD8B identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CD8B
Molecular Function
    protein binding GO:0005515 IPI
    coreceptor activity GO:0015026 NAS
    MHC class I protein binding GO:0042288 NAS
Biological Process
    regulation of defense response to virus by virus GO:0050690 TAS
    T cell activation GO:0042110 NAS
    immune response GO:0006955 NAS
    regulation of immune response GO:0050776 TAS
    transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 NAS
    viral process GO:0016032 TAS
Subcellular Localization
    early endosome membrane GO:0031901 TAS
    plasma membrane GO:0005886 TAS
    integral component of plasma membrane GO:0005887 TAS
    extracellular region GO:0005576 IEA
    external side of plasma membrane GO:0009897 IEA
    T cell receptor complex GO:0042101 NAS
 Experiment description of studies that identified CD8B in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD8B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CD8A 925
Invivo Homo sapiens
Invitro Homo sapiens
Co-localization Homo sapiens
View the network image/svg+xml

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