Gene description for CEP68
Gene name centrosomal protein 68kDa
Gene symbol CEP68
Other names/aliases KIAA0582
Species Homo sapiens
 Database cross references - CEP68
ExoCarta ExoCarta_23177
Vesiclepedia VP_23177
Entrez Gene 23177
HGNC 29076
UniProt Q76N32  
 CEP68 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
 Gene ontology annotations for CEP68
Molecular Function
    protein binding GO:0005515 IPI
    protein kinase binding GO:0019901 IPI
    protein domain specific binding GO:0019904 IPI
Biological Process
    centrosome cycle GO:0007098 IMP
    centriole-centriole cohesion GO:0010457 IMP
    protein localization to organelle GO:0033365 IMP
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    centrosome GO:0005813 IDA
    cytosol GO:0005829 IDA
    cell junction GO:0030054 IDA
    centriolar satellite GO:0034451 IDA
 Experiment description of studies that identified CEP68 in exosomes
1
Experiment ID 234
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
2
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for CEP68
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LPXN 9404
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 TRIM54  
Two-hybrid Homo sapiens
3 CDK5RAP2 55755
Affinity Capture-Western Homo sapiens
4 Prkar2a 19087
Affinity Capture-MS Mus musculus
5 BTRC 8945
Affinity Capture-Western Homo sapiens
6 USHBP1  
Two-hybrid Homo sapiens
7 PCNT  
Affinity Capture-Western Homo sapiens
8 Uso1 56041
Affinity Capture-MS Mus musculus
9 USO1 8615
Affinity Capture-MS Homo sapiens
10 VHL  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
11 Prkacb 18749
Affinity Capture-MS Mus musculus
12 CTBP1 1487
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
13 PRKAR2B 5577
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CEP68 is involved
No pathways found





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