Gene description for CEP68
Gene name
centrosomal protein 68kDa
Gene symbol
CEP68
Other names/aliases
KIAA0582
Species
Homo sapiens
Database cross references - CEP68
ExoCarta
ExoCarta_23177
Vesiclepedia
VP_23177
Entrez Gene
23177
HGNC
29076
UniProt
Q76N32
CEP68 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Hepatocytes
26054723
Gene ontology annotations for CEP68
Experiment description of studies that identified CEP68 in exosomes
1
Experiment ID
234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-C3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocytes
Sample name
MIHA
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RNA Sequencing
Protein-protein interactions for CEP68
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
LPXN
9404
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
2
TRIM54
Two-hybrid
Homo sapiens
3
CDK5RAP2
55755
Affinity Capture-Western
Homo sapiens
4
Prkar2a
19087
Affinity Capture-MS
Mus musculus
5
BTRC
8945
Affinity Capture-Western
Homo sapiens
6
USHBP1
Two-hybrid
Homo sapiens
7
PCNT
Affinity Capture-Western
Homo sapiens
8
Uso1
56041
Affinity Capture-MS
Mus musculus
9
USO1
8615
Affinity Capture-MS
Homo sapiens
10
VHL
Affinity Capture-Western
Homo sapiens
Biochemical Activity
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
11
Prkacb
18749
Affinity Capture-MS
Mus musculus
12
CTBP1
1487
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
13
PRKAR2B
5577
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which CEP68 is involved
No pathways found