Gene description for Dcaf13
Gene name DDB1 and CUL4 associated factor 13
Gene symbol Dcaf13
Other names/aliases Gm83
Wdsof1
Species Mus musculus
 Database cross references - Dcaf13
ExoCarta ExoCarta_223499
Entrez Gene 223499
UniProt Q6PAC3  
 Dcaf13 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Dcaf13
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    biological_process GO:0008150 ND
    ribosome biogenesis GO:0042254 IEA
    rRNA processing GO:0006364 IEA
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000462 IBA
Subcellular Localization
    Cul4-RING E3 ubiquitin ligase complex GO:0080008 ISO
    nucleolus GO:0005730 IBA
    small-subunit processome GO:0032040 IBA
    nucleus GO:0005634 IEA
    ribonucleoprotein complex GO:0030529 IEA
 Experiment description of studies that identified Dcaf13 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Dcaf13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dcaf13 is involved
No pathways found





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