Gene description for RBM24
Gene name RNA binding motif protein 24
Gene symbol RBM24
Other names/aliases RNPC6
dJ259A10.1
Species Homo sapiens
 Database cross references - RBM24
ExoCarta ExoCarta_221662
Vesiclepedia VP_221662
Entrez Gene 221662
HGNC 21539
UniProt Q9BX46  
 RBM24 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for RBM24
Molecular Function
    mRNA 3'-UTR binding GO:0003730 IBA
    mRNA 3'-UTR binding GO:0003730 IDA
    mRNA 3'-UTR binding GO:0003730 ISS
    protein binding GO:0005515 IPI
    mRNA 3'-UTR AU-rich region binding GO:0035925 IDA
    pre-mRNA intronic binding GO:0097157 ISS
    mRNA CDS binding GO:1990715 IDA
    sequence-specific mRNA binding GO:1990825 IDA
Biological Process
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IBA
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IMP
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 ISS
    endocardial cushion development GO:0003197 IEA
    mRNA processing GO:0006397 IEA
    DNA damage response GO:0006974 IMP
    RNA splicing GO:0008380 IEA
    regulation of myotube differentiation GO:0010830 ISS
    positive regulation of myotube differentiation GO:0010831 IBA
    positive regulation of myotube differentiation GO:0010831 IMP
    cell differentiation GO:0030154 IEA
    regulation of mRNA stability GO:0043488 ISS
    positive regulation of myoblast differentiation GO:0045663 ISS
    mRNA stabilization GO:0048255 IBA
    mRNA stabilization GO:0048255 IMP
    mRNA destabilization GO:0061157 IMP
    3'-UTR-mediated mRNA destabilization GO:0061158 IDA
    positive regulation of skeletal muscle fiber differentiation GO:1902811 ISS
    positive regulation of 3'-UTR-mediated mRNA stabilization GO:1905870 IMP
    positive regulation of stem cell differentiation GO:2000738 IMP
    negative regulation of cytoplasmic translation GO:2000766 IMP
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified RBM24 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for RBM24
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RBM38  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 CALML3 810
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 TYMP 1890
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 MYCN  
Affinity Capture-MS Homo sapiens
5 PIK3IP1 113791
Affinity Capture-MS Homo sapiens
6 SERPINB3 6317
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 QSOX1 5768
Affinity Capture-MS Homo sapiens
8 IVL 3713
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 RBPMS 11030
Two-hybrid Homo sapiens
10 JUP 3728
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 DMKN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 CRYAB 1410
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 POU2AF1  
Two-hybrid Homo sapiens
14 SERPINB13 5275
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 EPPK1 83481
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 ANKRD40 91369
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 IGHG2 3501
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CREBBP  
Two-hybrid Homo sapiens
19 RBFOX1 54715
Two-hybrid Homo sapiens
20 PKP1 5317
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 SERPINB5 5268
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 DAZAP2  
Two-hybrid Homo sapiens
23 PPL 5493
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 MYC  
Affinity Capture-MS Homo sapiens
25 CALML5 51806
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 IGHG1 3500
Affinity Capture-MS Homo sapiens
27 UBQLN2 29978
Two-hybrid Homo sapiens
28 C10orf55  
Two-hybrid Homo sapiens
29 LGALS7B 653499
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 SERPINB2 5055
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 PLCD1 5333
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 EVPL 2125
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 SS18L2  
Affinity Capture-MS Homo sapiens
34 TRIM29 23650
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 H2AFY 9555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 PKP3 11187
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RBM24 is involved
No pathways found





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