Gene description for MYOZ2
Gene name myozenin 2
Gene symbol MYOZ2
Other names/aliases C4orf5
CMH16
CS-1
Species Homo sapiens
 Database cross references - MYOZ2
ExoCarta ExoCarta_51778
Entrez Gene 51778
HGNC 1330
MIM 605602
UniProt Q9NPC6  
 MYOZ2 identified in exosomes derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for MYOZ2
Molecular Function
    protein binding GO:0005515 IPI
    protein phosphatase 2B binding GO:0030346 NAS
    actin binding GO:0003779 IEA
    telethonin binding GO:0031433 IPI
Biological Process
    biological_process GO:0008150 ND
Subcellular Localization
    sarcomere GO:0030017 TAS
    actin cytoskeleton GO:0015629 IEA
    Z disc GO:0030018 NAS
 Experiment description of studies that identified MYOZ2 in exosomes
1
Experiment ID 193
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63|CD9
EV Membrane markers
PHB
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MYOZ2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PPP3CB  
Invivo Homo sapiens
2 FLNC 2318
Affinity Capture-Western Homo sapiens
3 ACTN1 87
Affinity Capture-MS Homo sapiens
4 PPP3CA 5530
Affinity Capture-MS Homo sapiens
5 EWSR1 2130
Two-hybrid Homo sapiens
6 ACTN4 81
Two-hybrid Homo sapiens
7 TCAP  
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which MYOZ2 is involved
No pathways found





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