Gene description for MYNN
Gene name myoneurin
Gene symbol MYNN
Other names/aliases OSZF
SBBIZ1
ZBTB31
ZNF902
Species Homo sapiens
 Database cross references - MYNN
ExoCarta ExoCarta_55892
Vesiclepedia VP_55892
Entrez Gene 55892
HGNC 14955
MIM 606042
UniProt Q9NPC7  
 MYNN identified in sEVs derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for MYNN
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    cellular response to leukemia inhibitory factor GO:1990830 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified MYNN in sEVs
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for MYNN
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 COPS5 10987
Affinity Capture-MS Homo sapiens
2 CAT 847
Cross-Linking-MS (XL-MS) Homo sapiens
3 CD6 923
Affinity Capture-MS Homo sapiens
4 CUL3 8452
Affinity Capture-MS Homo sapiens
5 USP7 7874
Affinity Capture-MS Homo sapiens
6 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
7 Mis12  
Affinity Capture-MS Mus musculus
8 NOTCH2 4853
Affinity Capture-MS Homo sapiens
9 PAK1 5058
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which MYNN is involved
No pathways found





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