Gene description for GRB10
Gene name	growth factor receptor-bound protein 10
Gene symbol	GRB10
Other names/aliases	GRB-IR Grb-10 IRBP MEG1 RSS
Species	Homo sapiens
Database cross references - GRB10
ExoCarta	ExoCarta_2887
Entrez Gene	2887
HGNC	4564
MIM	601523
UniProt	Q13322
GRB10 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for GRB10

Molecular Function     protein binding GO:0005515 IPI     insulin receptor binding GO:0005158 ISS     SH3/SH2 adaptor activity GO:0005070 IEA Biological Process     negative regulation of glucose import GO:0046325 ISS     negative regulation of Wnt signaling pathway GO:0030178 IDA     negative regulation of glycogen biosynthetic process GO:0045719 ISS     positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 IDA     response to insulin GO:0032868 ISS     positive regulation of phosphorylation GO:0042327 ISS     negative regulation of phosphorylation GO:0042326 IEA     negative regulation of insulin receptor signaling pathway GO:0046627 ISS     insulin receptor signaling pathway GO:0008286 TAS     insulin-like growth factor receptor signaling pathway GO:0048009 IEA Subcellular Localization     cytoplasm GO:0005737 TAS     plasma membrane GO:0005886 TAS     cytosol GO:0005829 TAS