Gene description for ANKS1B
Gene name ankyrin repeat and sterile alpha motif domain containing 1B
Gene symbol ANKS1B
Other names/aliases AIDA
AIDA-1
ANKS2
EB-1
EB1
cajalin-2
Species Homo sapiens
 Database cross references - ANKS1B
ExoCarta ExoCarta_56899
Entrez Gene 56899
HGNC 24600
MIM 607815
UniProt Q7Z6G8  
 ANKS1B identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for ANKS1B
Molecular Function
    ephrin receptor binding GO:0046875 IPI
Subcellular Localization
    cell junction GO:0030054 IEA
    postsynaptic density GO:0014069 IEA
    postsynaptic membrane GO:0045211 IEA
    dendritic spine GO:0043197 IEA
    Cajal body GO:0015030 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified ANKS1B in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for ANKS1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LRP2 4036
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ANKS1B is involved
No pathways found





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