Gene description for GNG10
Gene name guanine nucleotide binding protein (G protein), gamma 10
Gene symbol GNG10
Other names/aliases -
Species Homo sapiens
 Database cross references - GNG10
ExoCarta ExoCarta_2790
Entrez Gene 2790
HGNC 4402
MIM 604389
UniProt P50151  
 GNG10 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for GNG10
Molecular Function
    protein binding GO:0005515 IPI
    GTPase activity GO:0003924 TAS
    signal transducer activity GO:0004871 IEA
Biological Process
    small molecule metabolic process GO:0044281 TAS
    signal transduction GO:0007165 TAS
    synaptic transmission GO:0007268 TAS
    energy reserve metabolic process GO:0006112 TAS
    G-protein coupled receptor signaling pathway GO:0007186 IEA
    cellular response to glucagon stimulus GO:0071377 TAS
Subcellular Localization
    plasma membrane GO:0005886 TAS
    heterotrimeric G-protein complex GO:0005834 IEA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified GNG10 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GNG10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GNB1 2782
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
2 GNB2 2783
Reconstituted Complex Homo sapiens
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