Gene description for PARVG
Gene name parvin, gamma
Gene symbol PARVG
Other names/aliases -
Species Homo sapiens
 Database cross references - PARVG
ExoCarta ExoCarta_64098
Vesiclepedia VP_64098
Entrez Gene 64098
HGNC 14654
MIM 608122
UniProt Q9HBI0  
 PARVG identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
Thymus 23844026    
 Gene ontology annotations for PARVG
Molecular Function
    actin binding GO:0003779 IBA
    actin binding GO:0003779 TAS
    protein binding GO:0005515 IPI
Biological Process
    cell-matrix adhesion GO:0007160 TAS
    cell projection assembly GO:0030031 IBA
    actin cytoskeleton organization GO:0030036 IBA
    substrate adhesion-dependent cell spreading GO:0034446 IBA
    establishment or maintenance of cell polarity regulating cell shape GO:0071963 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoskeleton GO:0005856 TAS
    plasma membrane GO:0005886 IEA
    focal adhesion GO:0005925 IBA
    actin cytoskeleton GO:0015629 IBA
 Experiment description of studies that identified PARVG in exosomes
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
2
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PARVG
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 POLR2G 5436
Two-hybrid Homo sapiens
3 PDLIM7 9260
Two-hybrid Homo sapiens
4 GNG10 2790
Affinity Capture-MS Homo sapiens
5 CFAP53  
Two-hybrid Homo sapiens
6 SERTAD2 9792
Two-hybrid Homo sapiens
7 HOMEZ  
Two-hybrid Homo sapiens
8 POTEI 653269
Affinity Capture-MS Homo sapiens
9 FOSL1  
Two-hybrid Homo sapiens
10 MTX2 10651
Affinity Capture-MS Homo sapiens
11 GADD45A  
Two-hybrid Homo sapiens
12 NBPF22P  
Two-hybrid Homo sapiens
13 REL 5966
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
14 RSU1 6251
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 ASGR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 TSGA10IP  
Two-hybrid Homo sapiens
17 CDSN 1041
Two-hybrid Homo sapiens
18 STRN3 29966
Proximity Label-MS Homo sapiens
19 CD59 966
Affinity Capture-MS Homo sapiens
20 CSF3 1440
Two-hybrid Homo sapiens
21 ZNF426  
Two-hybrid Homo sapiens
22 AES 166
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
23 TRIM54  
Two-hybrid Homo sapiens
24 SULT4A1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 KCTD7 154881
Two-hybrid Homo sapiens
26 POLK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 POU6F2  
Two-hybrid Homo sapiens
28 CDHR3  
Two-hybrid Homo sapiens
29 NBPF6  
Two-hybrid Homo sapiens
30 FAM173A  
Two-hybrid Homo sapiens
31 GNB2 2783
Affinity Capture-MS Homo sapiens
32 KLHL32 114792
Two-hybrid Homo sapiens
33 LHX3  
Two-hybrid Homo sapiens
34 NDEL1 81565
Two-hybrid Homo sapiens
35 MEOX2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
36 USHBP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
37 ILK 3611
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
38 DDIT4L  
Two-hybrid Homo sapiens
39 AARSD1 80755
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 ZNF677  
Two-hybrid Homo sapiens
41 LIMS1 3987
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PARVG is involved
No pathways found





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