Gene description for MYO3B
Gene name myosin IIIB
Gene symbol MYO3B
Other names/aliases -
Species Homo sapiens
 Database cross references - MYO3B
ExoCarta ExoCarta_140469
Entrez Gene 140469
HGNC 15576
MIM 610040
UniProt Q8WXR4  
 MYO3B identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for MYO3B
Molecular Function
    ATP binding GO:0005524 IEA
    protein serine/threonine kinase activity GO:0004674 IEA
    actin binding GO:0003779 IEA
    microfilament motor activity GO:0000146 IEA
Biological Process
    visual perception GO:0007601 IEA
    response to stimulus GO:0050896 IEA
    protein autophosphorylation GO:0046777 IEA
    peptidyl-threonine phosphorylation GO:0018107 IEA
    positive regulation of filopodium assembly GO:0051491 IEA
    peptidyl-serine phosphorylation GO:0018105 IEA
Subcellular Localization
    photoreceptor inner segment GO:0001917 IEA
    myosin complex GO:0016459 IEA
    filopodium tip GO:0032433 IEA
    photoreceptor outer segment GO:0001750 IEA
    cytoplasm GO:0005737 IEA
    stereocilium bundle tip GO:0032426 IEA
 Experiment description of studies that identified MYO3B in exosomes
1
Experiment ID 191
ISEV standards
✘ EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD81|CD9
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MYO3B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MYO3B is involved
No pathways found





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