Gene description for GULP1
Gene name GULP, engulfment adaptor PTB domain containing 1
Gene symbol GULP1
Other names/aliases CED-6
CED6
GULP
Species Homo sapiens
 Database cross references - GULP1
ExoCarta ExoCarta_51454
Entrez Gene 51454
HGNC 18649
MIM 608165
UniProt Q9UBP9  
 GULP1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for GULP1
Molecular Function
    signal transducer activity GO:0004871 TAS
Biological Process
    apoptotic process GO:0006915 IEA
    lipid transport GO:0006869 IEA
    signal transduction GO:0007165 TAS
    phagocytosis, engulfment GO:0006911 IDA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified GULP1 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for GULP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LRP1 4035
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which GULP1 is involved
No pathways found





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