Gene description for CMYA5
Gene name cardiomyopathy associated 5
Gene symbol CMYA5
Other names/aliases C5orf10
Species Homo sapiens
 Database cross references - CMYA5
ExoCarta ExoCarta_202333
Entrez Gene 202333
HGNC 14305
MIM 612193
UniProt Q8N3K9  
 CMYA5 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for CMYA5
Molecular Function
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IEA
Biological Process
    negative regulation of protein phosphatase type 2B activity GO:0032513 IEA
    negative regulation of calcineurin-NFAT signaling cascade GO:0070885 IEA
    regulation of skeletal muscle adaptation GO:0014733 IEA
Subcellular Localization
    perinuclear region of cytoplasm GO:0048471 IEA
    M band GO:0031430 IEA
    costamere GO:0043034 IEA
 Experiment description of studies that identified CMYA5 in exosomes
Experiment ID 224
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for CMYA5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PSMC4 5704
Affinity Capture-MS Homo sapiens
2 BZW1 9689
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CMYA5 is involved
No pathways found

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