Gene description for Flna
Gene name	filamin, alpha
Gene symbol	Flna
Other names/aliases	ABP-280 Dilp2 F730004A14Rik Fln1 GENA 379 filamin-1
Species	Mus musculus
Database cross references - Flna
ExoCarta	ExoCarta_192176
Entrez Gene	192176
UniProt	Q8BTM8
Flna identified in exosomes derived from the following tissue/cell type
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846
Pancreatic cells	19351151

Gene ontology annotations for Flna

Molecular Function     protein binding GO:0005515 IPI     protein complex binding GO:0032403 ISO     Rho GTPase binding GO:0017048 ISO     Rac GTPase binding GO:0048365 ISO     signal transducer activity GO:0004871 ISO     actin binding GO:0003779 TAS     poly(A) RNA binding GO:0044822 ISO     Ral GTPase binding GO:0017160 ISO     SMAD binding GO:0046332 ISO     transcription factor binding GO:0008134 ISO     Fc-gamma receptor I complex binding GO:0034988 ISO     protein homodimerization activity GO:0042803 ISO     small GTPase binding GO:0031267 ISO     protein kinase C binding GO:0005080 IDA     actin filament binding GO:0051015 ISO     mu-type opioid receptor binding GO:0031852 ISO     glycoprotein binding GO:0001948 ISO Biological Process     adenylate cyclase-inhibiting dopamine receptor signaling pathway GO:0007195 ISO     negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433 ISO     establishment of protein localization GO:0045184 ISO     mitotic spindle assembly GO:0090307 ISO     actin crosslink formation GO:0051764 ISO     negative regulation of transcription from RNA polymerase I promoter GO:0016479 ISO     positive regulation of integrin-mediated signaling pathway GO:2001046 ISO     receptor clustering GO:0043113 ISO     actin cytoskeleton organization GO:0030036 IGI     protein stabilization GO:0050821 ISO     negative regulation of apoptotic process GO:0043066 ISO     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISO     epithelial to mesenchymal transition GO:0001837 IGI     negative regulation of protein catabolic process GO:0042177 ISO     early endosome to late endosome transport GO:0045022 IDA     actin cytoskeleton reorganization GO:0031532 ISO     positive regulation of substrate adhesion-dependent cell spreading GO:1900026 ISO     protein localization to cell surface GO:0034394 ISO     cytoplasmic sequestering of protein GO:0051220 ISO     positive regulation of transcription factor import into nucleus GO:0042993 ISO     platelet aggregation GO:0070527 ISO     mRNA transcription from RNA polymerase II promoter GO:0042789 ISO     cilium assembly GO:0042384 ISO     cell projection organization GO:0030030 IEA Subcellular Localization     trans-Golgi network GO:0005802 IDA     cytoskeleton GO:0005856 IEA     perinuclear region of cytoplasm GO:0048471 ISO     Myb complex GO:0031523 ISO     cortical cytoskeleton GO:0030863 ISO     nucleolar part GO:0044452 ISO     apical dendrite GO:0097440 ISO     plasma membrane GO:0005886 ISO     protein complex GO:0043234 ISO     cytoplasm GO:0005737 ISO     actin filament bundle GO:0032432 IDA     actin filament GO:0005884 ISO     brush border GO:0005903 IDA     neuronal cell body GO:0043025 ISO     dendritic shaft GO:0043198 ISO     membrane GO:0016020 ISO     extracellular exosome GO:0070062 ISO     nucleus GO:0005634 ISO     actin cytoskeleton GO:0015629 ISO     cytosol GO:0005829 ISO     focal adhesion GO:0005925 ISO