Gene description for POGK
Gene name pogo transposable element with KRAB domain
Gene symbol POGK
Other names/aliases BASS2
KRBOX2
LST003
Species Homo sapiens
 Database cross references - POGK
ExoCarta ExoCarta_57645
Entrez Gene 57645
HGNC 18800
UniProt Q9P215  
 POGK identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for POGK
Molecular Function
    DNA binding GO:0003677 IEA
    protein binding GO:0005515 IPI
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IEA
    multicellular organismal development GO:0007275 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified POGK in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for POGK
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which POGK is involved
No pathways found





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