Gene description for POGK
Gene name pogo transposable element with KRAB domain
Gene symbol POGK
Other names/aliases BASS2
KRBOX2
LST003
Species Homo sapiens
 Database cross references - POGK
ExoCarta ExoCarta_57645
Vesiclepedia VP_57645
Entrez Gene 57645
HGNC 18800
UniProt Q9P215  
 POGK identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for POGK
Molecular Function
    DNA binding GO:0003677 IBA
    protein binding GO:0005515 IPI
Biological Process
    regulation of DNA-templated transcription GO:0006355 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified POGK in exosomes
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for POGK
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 CCNDBP1 23582
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 Trim28 21849
Affinity Capture-MS Mus musculus
4 NPAS1  
Affinity Capture-MS Homo sapiens
5 S100P 6286
Affinity Capture-MS Homo sapiens
6 PRKY  
Affinity Capture-MS Homo sapiens
7 METTL10  
Affinity Capture-MS Homo sapiens
8 ARPC1B 10095
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 CUL3 8452
Affinity Capture-MS Homo sapiens
10 ARL2BP 23568
Affinity Capture-MS Homo sapiens
11 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
12 HSP90AA1 3320
Affinity Capture-Luminescence Homo sapiens
13 TCEAL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 UCHL3 7347
Two-hybrid Homo sapiens
15 WEE1 7465
Affinity Capture-MS Homo sapiens
16 CBX3 11335
Proximity Label-MS Homo sapiens
17 ZNF44  
Affinity Capture-MS Homo sapiens
18 C12orf74  
Affinity Capture-MS Homo sapiens
19 TRIM28 10155
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 ZNF333  
Affinity Capture-MS Homo sapiens
21 RFXANK  
Affinity Capture-MS Homo sapiens
22 NAA11 84779
Affinity Capture-MS Homo sapiens
23 TRIM11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 PTGES3 10728
Affinity Capture-MS Homo sapiens
25 UBXN6 80700
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which POGK is involved
No pathways found





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