Gene description for RUSC2
Gene name RUN and SH3 domain containing 2
Gene symbol RUSC2
Other names/aliases Iporin
Species Homo sapiens
 Database cross references - RUSC2
ExoCarta ExoCarta_9853
Entrez Gene 9853
HGNC 23625
MIM 611053
UniProt Q8N2Y8  
 RUSC2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for RUSC2
Molecular Function
    protein binding GO:0005515 IPI
    Rab GTPase binding GO:0017137 IPI
Biological Process
    biological_process GO:0008150 ND
Subcellular Localization
    cytosol GO:0005829 IEA
    cytoplasmic vesicle GO:0031410 IDA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified RUSC2 in exosomes
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for RUSC2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DLST 1743
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RUSC2 is involved
No pathways found

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