Gene description for MAP1S
Gene name microtubule-associated protein 1S
Gene symbol MAP1S
Other names/aliases BPY2IP1
Species Homo sapiens
 Database cross references - MAP1S
ExoCarta ExoCarta_55201
Entrez Gene 55201
HGNC 15715
MIM 607573
UniProt Q66K74  
 MAP1S identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for MAP1S
Molecular Function
    actin filament binding GO:0051015 IDA
    beta-tubulin binding GO:0048487 IDA
    DNA binding GO:0003677 IDA
    identical protein binding GO:0042802 IEA
    microtubule binding GO:0008017 TAS
    deoxyribonuclease activity GO:0004536 IDA
    tubulin binding GO:0015631 IDA
    protein binding GO:0005515 IPI
Biological Process
    microtubule bundle formation GO:0001578 IMP
    brain development GO:0007420 ISS
    mitochondrion transport along microtubule GO:0047497 TAS
    nervous system development GO:0007399 ISS
    autophagy GO:0006914 TAS
    apoptotic process GO:0006915 IEA
    neuron projection morphogenesis GO:0048812 IEP
    regulation of chromatin disassembly GO:0010848 IDA
Subcellular Localization
    nucleolus GO:0005730 IDA
    perinuclear region of cytoplasm GO:0048471 IDA
    cell projection GO:0042995 IDA
    spindle GO:0005819 IEA
    dendrite GO:0030425 ISS
    synapse GO:0045202 IDA
    microtubule GO:0005874 IDA
    nucleus GO:0005634 IDA
    neuronal cell body GO:0043025 ISS
    cytosol GO:0005829 IDA
    cytoplasm GO:0005737 IDA
    cell junction GO:0030054 IDA
 Experiment description of studies that identified MAP1S in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MAP1S
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Rassf1  
Two-hybrid Mus musculus
Affinity Capture-Western Mus musculus
2 LRPPRC 10128
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
3 BPY2  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
4 COX1  
Two-hybrid Homo sapiens
5 RASSF1  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
6 ND1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which MAP1S is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here