Gene description for STK4
Gene name serine/threonine kinase 4
Gene symbol STK4
Other names/aliases KRS2
MST1
TIIAC
YSK3
Species Homo sapiens
 Database cross references - STK4
ExoCarta ExoCarta_6789
Vesiclepedia VP_6789
Entrez Gene 6789
HGNC 11408
MIM 604965
UniProt Q13043  
 STK4 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocytes 26054723    
Thymus 23844026    
 Gene ontology annotations for STK4
Molecular Function
    magnesium ion binding GO:0000287 IDA
    protein kinase activity GO:0004672 IGI
    protein serine/threonine kinase activity GO:0004674 EXP
    protein serine/threonine kinase activity GO:0004674 IBA
    protein serine/threonine kinase activity GO:0004674 IDA
    3-phosphoinositide-dependent protein kinase activity GO:0004676 IEA
    DNA-dependent protein kinase activity GO:0004677 IEA
    AMP-activated protein kinase activity GO:0004679 IEA
    eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 IEA
    ribosomal protein S6 kinase activity GO:0004711 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IDA
    histone H3S10 kinase activity GO:0035175 IEA
    histone H3T11 kinase activity GO:0035402 IEA
    histone H3T6 kinase activity GO:0035403 IEA
    histone H2AXS139 kinase activity GO:0035979 IEA
    identical protein binding GO:0042802 IPI
    protein homodimerization activity GO:0042803 IDA
    protein serine/threonine kinase activator activity GO:0043539 TAS
    histone H3S28 kinase activity GO:0044022 IEA
    histone H4S1 kinase activity GO:0044023 IEA
    histone H2AS1 kinase activity GO:0044024 IEA
    histone H2BS14 kinase activity GO:0044025 IEA
    RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IPI
    histone H3T3 kinase activity GO:0072354 IEA
    histone H2AS121 kinase activity GO:0072371 IEA
    Rho-dependent protein serine/threonine kinase activity GO:0072518 IEA
    protein serine kinase activity GO:0106310 IEA
    histone H2BS36 kinase activity GO:0140823 IEA
    histone H3S57 kinase activity GO:0140855 IEA
    histone H3T45 kinase activity GO:0140857 IEA
    histone H2AT120 kinase activity GO:1990244 IEA
Biological Process
    cell morphogenesis GO:0000902 IDA
    branching involved in blood vessel morphogenesis GO:0001569 IEA
    neural tube formation GO:0001841 IEA
    positive regulation of protein phosphorylation GO:0001934 IDA
    endocardium development GO:0003157 IEA
    chromatin remodeling GO:0006338 IEA
    protein phosphorylation GO:0006468 IDA
    protein phosphorylation GO:0006468 IDA
    protein import into nucleus GO:0006606 IDA
    protein import into nucleus GO:0006606 IGI
    apoptotic process GO:0006915 IDA
    signal transduction GO:0007165 TAS
    central nervous system development GO:0007417 IEA
    extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 IEA
    peptidyl-serine phosphorylation GO:0018105 IDA
    keratinocyte differentiation GO:0030216 IEA
    positive regulation of peptidyl-serine phosphorylation GO:0033138 IDA
    organ growth GO:0035265 IEA
    hippo signaling GO:0035329 IDA
    hippo signaling GO:0035329 TAS
    positive regulation of hippo signaling GO:0035332 IDA
    intracellular signal transduction GO:0035556 IBA
    intracellular signal transduction GO:0035556 IDA
    positive regulation of apoptotic process GO:0043065 IBA
    positive regulation of apoptotic process GO:0043065 IDA
    regulation of MAPK cascade GO:0043408 IBA
    positive regulation of fat cell differentiation GO:0045600 IEA
    negative regulation of organ growth GO:0046621 IEA
    protein autophosphorylation GO:0046777 IDA
    epithelial cell proliferation GO:0050673 IEA
    negative regulation of epithelial cell proliferation GO:0050680 IEA
    protein stabilization GO:0050821 IDA
    protein tetramerization GO:0051262 IEA
    canonical Wnt signaling pathway GO:0060070 IEA
    primitive hemopoiesis GO:0060215 IEA
    cell differentiation involved in embryonic placenta development GO:0060706 IEA
    regulation of cell differentiation involved in embryonic placenta development GO:0060800 IEA
    negative regulation of canonical Wnt signaling pathway GO:0090090 IBA
    negative regulation of canonical Wnt signaling pathway GO:0090090 IMP
    hepatocyte apoptotic process GO:0097284 IEA
    positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 IEA
    positive regulation of hepatocyte apoptotic process GO:1903945 IEA
    positive regulation of substrate-dependent cell migration, cell attachment to substrate GO:1904237 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    nuclear body GO:0016604 IDA
    protein-containing complex GO:0032991 IDA
 Experiment description of studies that identified STK4 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
9
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for STK4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 HIST2H2BE 8349
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
3 CNKSR1  
Affinity Capture-Western Homo sapiens
4 CDK3 1018
Affinity Capture-MS Homo sapiens
5 CCDC174  
Affinity Capture-MS Homo sapiens
6 VAPA 9218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 PAEP  
Affinity Capture-MS Homo sapiens
8 AKAP12 9590
Affinity Capture-MS Homo sapiens
9 IGHM 3507
Affinity Capture-MS Homo sapiens
10 STRN3 29966
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 TDRD3  
Affinity Capture-MS Homo sapiens
12 KDM4A  
Affinity Capture-MS Homo sapiens
13 S100A13 6284
Co-fractionation Homo sapiens
14 HSPA5 3309
Affinity Capture-MS Homo sapiens
15 MAP1LC3B 81631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
16 PARK2  
Affinity Capture-MS Homo sapiens
17 STRN 6801
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CASP3 836
Co-localization Homo sapiens
19 RASSF6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 ERC1 23085
Affinity Capture-MS Homo sapiens
21 PSMD12 5718
Co-fractionation Homo sapiens
22 ADCYAP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 NR4A1  
Affinity Capture-MS Homo sapiens
24 KIF2C 11004
Affinity Capture-MS Homo sapiens
25 ATG16L1 55054
Affinity Capture-MS Homo sapiens
26 STRIP1 85369
Proximity Label-MS Homo sapiens
27 ATP5H 10476
Affinity Capture-MS Homo sapiens
28 EMB 133418
Affinity Capture-MS Homo sapiens
29 BTRC 8945
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 ZNF554  
Affinity Capture-MS Homo sapiens
31 CTTNBP2NL  
Affinity Capture-Western Homo sapiens
32 NEDD4 4734
Reconstituted Complex Homo sapiens
33 KIF14 9928
Affinity Capture-MS Homo sapiens
34 RASSF2 9770
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 STOML2 30968
Affinity Capture-MS Homo sapiens
36 RNF6  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
37 ZNF133  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 MOB4 25843
Proximity Label-MS Homo sapiens
39 TAOK1 57551
Affinity Capture-MS Homo sapiens
40 MAP1B 4131
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 SGMS1  
Biochemical Activity Homo sapiens
42 PSMD14 10213
Co-fractionation Homo sapiens
43 CCDC96  
Affinity Capture-MS Homo sapiens
44 KIAA1683  
Affinity Capture-MS Homo sapiens
45 GABARAP 11337
Affinity Capture-Western Homo sapiens
46 RASSF5 83593
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 ACTR3B 57180
Affinity Capture-MS Homo sapiens
48 CLEC11A 6320
Affinity Capture-MS Homo sapiens
49 SLX4IP  
Affinity Capture-MS Homo sapiens
50 LATS2 26524
Affinity Capture-MS Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
51 DAXX  
Reconstituted Complex Homo sapiens
52 KIF3B 9371
Affinity Capture-MS Homo sapiens
53 STK3 6788
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 OGT 8473
Reconstituted Complex Homo sapiens
55 MOB1B 92597
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
56 VAPB 9217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 ABT1 29777
Affinity Capture-MS Homo sapiens
58 XPO1 7514
Affinity Capture-MS Homo sapiens
59 AKAP9 10142
Affinity Capture-MS Homo sapiens
60 ANXA1 301
Affinity Capture-MS Homo sapiens
61 S100A7 6278
Affinity Capture-MS Homo sapiens
62 DMXL1 1657
Affinity Capture-MS Homo sapiens
63 RASSF1  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 RASSF3 283349
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 ITPRIP  
Affinity Capture-MS Homo sapiens
66 SPCS3 60559
Affinity Capture-MS Homo sapiens
67 XPO6 23214
Affinity Capture-MS Homo sapiens
68 AURKB 9212
Affinity Capture-MS Homo sapiens
69 CRYBB3  
Affinity Capture-MS Homo sapiens
70 SAV1  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 ITPRIPL1  
Affinity Capture-MS Homo sapiens
72 SH3GLB2 56904
Proximity Label-MS Homo sapiens
73 DYRK2 8445
Affinity Capture-MS Homo sapiens
74 STK4 6789
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
75 KIF3C 3797
Affinity Capture-MS Homo sapiens
76 NDUFV2 4729
Affinity Capture-MS Homo sapiens
77 SLMAP 7871
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 KIF2B 84643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 SNX5 27131
Proximity Label-MS Homo sapiens
80 H2AFX 3014
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
81 KIF2A 3796
Affinity Capture-MS Homo sapiens
82 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
83 FBXW11  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 FOXO3  
Affinity Capture-Western Homo sapiens
85 RASSF4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 ZNF695  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 TP53 7157
Co-localization Homo sapiens
88 MAP1S 55201
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 STRN4 29888
Proximity Label-MS Homo sapiens
90 RNF31 55072
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
91 IL2RG  
Two-hybrid Homo sapiens
92 CDC37 11140
Affinity Capture-MS Homo sapiens
93 CUL5 8065
Affinity Capture-MS Homo sapiens
94 ABL1 25
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
95 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
96 IGHG2 3501
Affinity Capture-MS Homo sapiens
97 DDIT4L  
Two-hybrid Homo sapiens
98 SIRT1  
Biochemical Activity Homo sapiens
99 LATS1  
Biochemical Activity Homo sapiens
100 Rassf1  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
101 RAB8A 4218
Proximity Label-MS Homo sapiens
102 MAP1LC3A 84557
Affinity Capture-MS Homo sapiens
103 FGFR1OP2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 SPCS2 9789
Affinity Capture-MS Homo sapiens
105 CUL7 9820
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
106 MOB1A 55233
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
107 CAPN10  
Affinity Capture-MS Homo sapiens
108 PRKRIR  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
109 SLITRK6  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which STK4 is involved
PathwayEvidenceSource
Signal Transduction TAS Reactome
Signaling by Hippo TAS Reactome





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