Gene description for CAMSAP1
Gene name calmodulin regulated spectrin-associated protein 1
Gene symbol CAMSAP1
Other names/aliases PRO2405
bA100C15.1
Species Homo sapiens
 Database cross references - CAMSAP1
ExoCarta ExoCarta_157922
Vesiclepedia VP_157922
Entrez Gene 157922
HGNC 19946
MIM 613774
UniProt Q5T5Y3  
 CAMSAP1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for CAMSAP1
Molecular Function
    protein binding GO:0005515 IPI
    calmodulin binding GO:0005516 ISS
    microtubule binding GO:0008017 IDA
    spectrin binding GO:0030507 IDA
    microtubule minus-end binding GO:0051011 IDA
Biological Process
    microtubule cytoskeleton organization GO:0000226 IDA
    cytoskeleton organization GO:0007010 IMP
    regulation of cell morphogenesis GO:0022604 IMP
    regulation of microtubule polymerization GO:0031113 IDA
    neuron projection development GO:0031175 IGI
    neuron projection development GO:0031175 IMP
Subcellular Localization
    cytoplasm GO:0005737 IEA
    microtubule GO:0005874 IDA
    microtubule minus-end GO:0036449 IDA
 Experiment description of studies that identified CAMSAP1 in exosomes
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for CAMSAP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CTAG1A  
Two-hybrid Homo sapiens
2 REEP5 7905
Proximity Label-MS Homo sapiens
3 RNF43  
Proximity Label-MS Homo sapiens
4 KIF2A 3796
Proximity Label-MS Homo sapiens
5 FBXL6  
Proximity Label-MS Homo sapiens
6 MFHAS1 9258
Affinity Capture-MS Homo sapiens
7 SIRT6  
Affinity Capture-MS Homo sapiens
8 CLIP1 6249
Proximity Label-MS Homo sapiens
9 KIF3A 11127
Affinity Capture-MS Homo sapiens
10 SKIL  
Two-hybrid Homo sapiens
11 RBPJ 3516
Affinity Capture-MS Homo sapiens
12 METTL7A 25840
Proximity Label-MS Homo sapiens
13 NINL  
Proximity Label-MS Homo sapiens
14 KRT8 3856
Proximity Label-MS Homo sapiens
15 MEX3A  
Affinity Capture-RNA Homo sapiens
16 YWHAZ 7534
Affinity Capture-MS Homo sapiens
17 STIM1 6786
Proximity Label-MS Homo sapiens
18 TUBB4B 10383
Affinity Capture-MS Homo sapiens
19 CAMSAP2  
Proximity Label-MS Homo sapiens
20 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
21 CTAG1B  
Two-hybrid Homo sapiens
22 MAPRE1 22919
Proximity Label-MS Homo sapiens
23 SMAD1 4086
Two-hybrid Homo sapiens
24 MAPRE3  
Proximity Label-MS Homo sapiens
25 MRFAP1L1  
Affinity Capture-MS Homo sapiens
26 TRIM37  
Proximity Label-MS Homo sapiens
27 STK11 6794
Negative Genetic Homo sapiens
28 SMAD9  
Two-hybrid Homo sapiens
29 DYRK1A 1859
Affinity Capture-MS Homo sapiens
30 NTRK1 4914
Affinity Capture-MS Homo sapiens
31 PXN 5829
Proximity Label-MS Homo sapiens
32 DCTN1 1639
Proximity Label-MS Homo sapiens
33 NDC80 10403
Proximity Label-MS Homo sapiens
34 BICD2 23299
Proximity Label-MS Homo sapiens
35 PCM1 5108
Proximity Label-MS Homo sapiens
36 PRKAR1B  
Two-hybrid Homo sapiens
37 RPA3 6119
Proximity Label-MS Homo sapiens
38 NIN 51199
Proximity Label-MS Homo sapiens
39 C17orf59 54785
Proximity Label-MS Homo sapiens
40 DERL1 79139
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CAMSAP1 is involved
No pathways found





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