Gene description for FBXO24
Gene name F-box protein 24
Gene symbol FBXO24
Other names/aliases FBX24
Species Homo sapiens
 Database cross references - FBXO24
ExoCarta ExoCarta_26261
Vesiclepedia VP_26261
Entrez Gene 26261
HGNC 13595
MIM 609097
UniProt O75426  
 FBXO24 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for FBXO24
Molecular Function
    ubiquitin-protein transferase activity GO:0004842 NAS
    protein binding GO:0005515 IPI
Biological Process
    protein ubiquitination GO:0016567 NAS
Subcellular Localization
    ubiquitin ligase complex GO:0000151 NAS
 Experiment description of studies that identified FBXO24 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for FBXO24
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FAM192A  
Affinity Capture-MS Homo sapiens
2 NUDCD2 134492
Affinity Capture-MS Homo sapiens
3 CUL1 8454
Affinity Capture-Western Homo sapiens
4 SKP1 6500
Affinity Capture-Western Homo sapiens
5 PRMT6  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
6 NME1 4830
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
7 HSP90AA1 3320
Affinity Capture-Luminescence Homo sapiens
8 PSME3 10197
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FBXO24 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here