Gene description for DNPH1
Gene name 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Gene symbol DNPH1
Other names/aliases C6orf108
RCL
dJ330M21.3
Species Homo sapiens
 Database cross references - DNPH1
ExoCarta ExoCarta_10591
Entrez Gene 10591
HGNC 21218
UniProt O43598  
 DNPH1 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for DNPH1
Molecular Function
    nucleoside deoxyribosyltransferase activity GO:0050144 IEA
    deoxyribonucleoside 5'-monophosphate N-glycosidase activity GO:0070694 ISS
    protein homodimerization activity GO:0042803 IEA
Biological Process
    cell proliferation GO:0008283 TAS
    epithelial cell differentiation GO:0030855 IEP
    nucleoside metabolic process GO:0009116 IEA
    deoxyribonucleoside monophosphate catabolic process GO:0009159 ISS
    nucleotide metabolic process GO:0009117 IEA
    positive regulation of cell growth GO:0030307 ISS
Subcellular Localization
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 ISS
    extracellular exosome GO:0070062 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified DNPH1 in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for DNPH1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DNPH1 10591
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which DNPH1 is involved
No pathways found





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