Gene description for KCTD15
Gene name potassium channel tetramerization domain containing 15
Gene symbol KCTD15
Other names/aliases -
Species Homo sapiens
 Database cross references - KCTD15
ExoCarta ExoCarta_79047
Entrez Gene 79047
HGNC 23297
MIM 615240
UniProt Q96SI1  
 KCTD15 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for KCTD15
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    protein homooligomerization GO:0051260 IEA
    multicellular organismal development GO:0007275 IEA
 Experiment description of studies that identified KCTD15 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for KCTD15
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 REN  
Two-hybrid Homo sapiens
2 WIPI49  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which KCTD15 is involved
No pathways found





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