Gene description for NUB1
Gene name negative regulator of ubiquitin-like proteins 1
Gene symbol NUB1
Other names/aliases BS4
NUB1L
NYREN18
Species Homo sapiens
 Database cross references - NUB1
ExoCarta ExoCarta_51667
Entrez Gene 51667
HGNC 17623
MIM 607981
UniProt Q9Y5A7  
 NUB1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for NUB1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 IMP
    protein ubiquitination GO:0016567 IMP
    response to interferon-gamma GO:0034341 IEP
    response to tumor necrosis factor GO:0034612 IEP
    ubiquitin-dependent protein catabolic process GO:0006511 IMP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    nucleolus GO:0005730 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified NUB1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NUB1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AIPL1  
Two-hybrid Homo sapiens
2 PSMD4 5710
Reconstituted Complex Homo sapiens
3 FANCA  
Two-hybrid Homo sapiens
4 UBD  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
5 NEDD8 4738
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which NUB1 is involved
No pathways found





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