Gene description for PITPNM3
Gene name PITPNM family member 3
Gene symbol PITPNM3
Other names/aliases ACKR6
CORD5
NIR1
RDGBA3
Species Homo sapiens
 Database cross references - PITPNM3
ExoCarta ExoCarta_83394
Entrez Gene 83394
HGNC 21043
MIM 608921
UniProt Q9BZ71  
 PITPNM3 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for PITPNM3
Molecular Function
    phosphatidylinositol transporter activity GO:0008526 TAS
    lipid binding GO:0008289 IEA
    protein binding GO:0005515 IPI
    receptor tyrosine kinase binding GO:0030971 TAS
    calcium ion binding GO:0005509 TAS
Biological Process
    phosphatidylinositol metabolic process GO:0046488 TAS
    phospholipid transport GO:0015914 TAS
Subcellular Localization
    intracellular GO:0005622 IEA
    integral component of membrane GO:0016021 TAS
    endomembrane system GO:0012505 IEA
 Experiment description of studies that identified PITPNM3 in exosomes
1
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for PITPNM3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PTK2B 2185
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which PITPNM3 is involved
No pathways found





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