Gene description for SYNRG
Gene name synergin, gamma
Gene symbol SYNRG
Other names/aliases AP1GBP1
SYNG
Species Homo sapiens
 Database cross references - SYNRG
ExoCarta ExoCarta_11276
Vesiclepedia VP_11276
Entrez Gene 11276
HGNC 557
MIM 607291
UniProt Q9UMZ2  
 SYNRG identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for SYNRG
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    intracellular protein transport GO:0006886 TAS
    endocytosis GO:0006897 IEA
Subcellular Localization
    cytoplasm GO:0005737 TAS
    Golgi apparatus GO:0005794 TAS
    AP-1 adaptor complex GO:0030121 TAS
    clathrin coat of trans-Golgi network vesicle GO:0030130 IBA
    perinuclear region of cytoplasm GO:0048471 IEA
 Experiment description of studies that identified SYNRG in exosomes
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SYNRG
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GTSE1 51512
Affinity Capture-MS Homo sapiens
2 GGA3 23163
Protein-peptide Homo sapiens
3 AP2B1 163
Proximity Label-MS Homo sapiens
4 VAPA 9218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 VAPB 9217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 FBXL6  
Proximity Label-MS Homo sapiens
7 LAMTOR1 55004
Proximity Label-MS Homo sapiens
8 XPO1 7514
Affinity Capture-MS Homo sapiens
9 AP1S2 8905
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 RAB4A 5867
Proximity Label-MS Homo sapiens
11 SCAMP1 9522
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
12 AURKA 6790
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 ATG9A 79065
Proximity Label-MS Homo sapiens
14 HSPA1A 3303
Affinity Capture-MS Homo sapiens
15 ARHGAP18 93663
Affinity Capture-MS Homo sapiens
16 HOOK3 84376
Proximity Label-MS Homo sapiens
17 PFN1 5216
Proximity Label-MS Homo sapiens
18 CLTB 1212
Proximity Label-MS Homo sapiens
19 AFTPH  
Affinity Capture-MS Homo sapiens
20 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
21 AP1G2 8906
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 APPBP2  
Two-hybrid Homo sapiens
23 MLF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 SQSTM1 8878
Proximity Label-MS Homo sapiens
25 MYO6 4646
Proximity Label-MS Homo sapiens
26 AP1M2 10053
Affinity Capture-MS Homo sapiens
27 CLTA 1211
Proximity Label-MS Homo sapiens
28 AP1G1 164
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
29 AP1B1 162
Affinity Capture-MS Homo sapiens
30 PTPN23 25930
Proximity Label-MS Homo sapiens
31 GGA2 23062
Affinity Capture-Western Homo sapiens
32 AP1S3  
Affinity Capture-MS Homo sapiens
33 GGA1 26088
Two-hybrid Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
34 BIN1 274
Co-fractionation Homo sapiens
35 STX6 10228
Proximity Label-MS Homo sapiens
36 PIN4 5303
Affinity Capture-MS Homo sapiens
37 RAB11A 8766
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SYNRG is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here