Gene description for LEPROTL1
Gene name leptin receptor overlapping transcript-like 1
Gene symbol LEPROTL1
Other names/aliases HSPC112
Vps55
my047
Species Homo sapiens
 Database cross references - LEPROTL1
ExoCarta ExoCarta_23484
Entrez Gene 23484
HGNC 6555
MIM 607338
UniProt O95214  
 LEPROTL1 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for LEPROTL1
Subcellular Localization
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified LEPROTL1 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for LEPROTL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KLRG1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which LEPROTL1 is involved
No pathways found





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