Experiment description of studies that identified TMEM50B in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for TMEM50B

Protein Interactor ExoCarta ID Identification method PubMed Species 1 TMEM52B 120939 Two-hybrid Homo sapiens 2 CLRN1   Two-hybrid Homo sapiens 3 BCL2L1 598 Two-hybrid Homo sapiens 4 FAM209A 200232 Two-hybrid Homo sapiens 5 TMEM14B   Two-hybrid Homo sapiens 6 GPR152   Two-hybrid Homo sapiens 7 EDA   Two-hybrid Homo sapiens 8 AMIGO1   Two-hybrid Homo sapiens 9 TMEM88   Two-hybrid Homo sapiens 10 SLC10A6   Two-hybrid Homo sapiens 11 GPX8 493869 Two-hybrid Homo sapiens 12 HLA-DPA1   Two-hybrid Homo sapiens 13 SCN3B   Two-hybrid Homo sapiens 14 LEPROTL1 23484 Two-hybrid Homo sapiens 15 SLC16A13 201232 Two-hybrid Homo sapiens 16 NCR1   Two-hybrid Homo sapiens 17 LHFPL5   Two-hybrid Homo sapiens 18 TMX2 51075 Two-hybrid Homo sapiens 19 CREB3L1   Two-hybrid Homo sapiens View the network

Pathways in which TMEM50B is involved

No pathways found