Gene description for PDE12
Gene name phosphodiesterase 12
Gene symbol PDE12
Other names/aliases 2'-PDE
Species Homo sapiens
 Database cross references - PDE12
ExoCarta ExoCarta_201626
Entrez Gene 201626
HGNC 25386
UniProt Q6L8Q7  
 PDE12 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PDE12
Molecular Function
    metal ion binding GO:0046872 IEA
    poly(A)-specific ribonuclease activity GO:0004535 IEA
Biological Process
    RNA phosphodiester bond hydrolysis, exonucleolytic GO:0090503 IEA
    mRNA processing GO:0006397 IEA
Subcellular Localization
    mitochondrial matrix GO:0005759 IEA
 Experiment description of studies that identified PDE12 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PDE12
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PDE12 is involved
No pathways found





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