Gene description for PHF14
Gene name PHD finger protein 14
Gene symbol PHF14
Other names/aliases -
Species Homo sapiens
 Database cross references - PHF14
ExoCarta ExoCarta_9678
Entrez Gene 9678
HGNC 22203
UniProt O94880  
 PHF14 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for PHF14
Molecular Function
    zinc ion binding GO:0008270 IEA
Biological Process
    negative regulation of platelet-derived growth factor receptor-alpha signaling pathway GO:2000584 IEA
    lung alveolus development GO:0048286 IEA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA
    negative regulation of mesenchymal cell proliferation involved in lung development GO:2000791 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified PHF14 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for PHF14
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PHF14 is involved
No pathways found





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