Gene description for NAB1
Gene name NGFI-A binding protein 1 (EGR1 binding protein 1)
Gene symbol NAB1
Other names/aliases -
Species Homo sapiens
 Database cross references - NAB1
ExoCarta ExoCarta_4664
Entrez Gene 4664
HGNC 7626
MIM 600800
UniProt Q13506  
 NAB1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for NAB1
Molecular Function
    transcription factor binding GO:0008134 IEA
Biological Process
    Schwann cell differentiation GO:0014037 IEA
    myelination GO:0042552 IEA
    regulation of epidermis development GO:0045682 IEA
    negative regulation of transcription, DNA-templated GO:0045892 NAS
    regulation of transcription, DNA-templated GO:0006355 NAS
    endochondral ossification GO:0001958 IEA
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nucleus GO:0005634 NAS
 Experiment description of studies that identified NAB1 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for NAB1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EGR1  
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which NAB1 is involved
No pathways found





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