Gene description for THRB
Gene name	thyroid hormone receptor, beta
Gene symbol	THRB
Other names/aliases	C-ERBA-2 C-ERBA-BETA ERBA2 GRTH NR1A2 PRTH THR1 THRB1 THRB2
Species	Homo sapiens
Database cross references - THRB
ExoCarta	ExoCarta_7068
Entrez Gene	7068
HGNC	11799
MIM	190160
UniProt	P10828
THRB identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723

Gene ontology annotations for THRB

Molecular Function     thyroid hormone binding GO:0070324 IDA     protein binding GO:0005515 IPI     DNA binding GO:0003677 TAS     steroid hormone receptor activity GO:0003707 IEA     chromatin DNA binding GO:0031490 IEA     enzyme binding GO:0019899 IPI     transcription corepressor activity GO:0003714 TAS     sequence-specific DNA binding transcription factor activity GO:0003700 NAS     zinc ion binding GO:0008270 IEA     thyroid hormone receptor activity GO:0004887 IDA     sequence-specific DNA binding GO:0043565 IEA Biological Process     organ morphogenesis GO:0009887 IEA     negative regulation of female receptivity GO:0007621 IEA     transcription, DNA-templated GO:0006351 TAS     female courtship behavior GO:0008050 IEA     transcription initiation from RNA polymerase II promoter GO:0006367 TAS     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA     Type I pneumocyte differentiation GO:0060509 IEA     sensory perception of sound GO:0007605 IEA     gene expression GO:0010467 TAS     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA     regulation of heart contraction GO:0008016 IEA     intracellular receptor signaling pathway GO:0030522 TAS     steroid hormone mediated signaling pathway GO:0043401 IEA Subcellular Localization     extracellular exosome GO:0070062 IDA     nucleoplasm GO:0005654 TAS     nuclear chromatin GO:0000790 IEA     nucleus GO:0005634 TAS