Gene description for PFKFB2
Gene name	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Gene symbol	PFKFB2
Other names/aliases	PFK-2/FBPase-2
Species	Homo sapiens
Database cross references - PFKFB2
ExoCarta	ExoCarta_5208
Entrez Gene	5208
HGNC	8873
MIM	171835
UniProt	O60825
PFKFB2 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for PFKFB2

Molecular Function     fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 IEA     6-phosphofructo-2-kinase activity GO:0003873 IDA     protein kinase binding GO:0019901 IPI     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA Biological Process     fructose metabolic process GO:0006000 IEA     positive regulation of insulin secretion GO:0032024 IEA     glycolytic process GO:0006096 IDA     lactate metabolic process GO:0006089 IEA     dephosphorylation GO:0016311 IEA     carbohydrate metabolic process GO:0005975 TAS     positive regulation of glucokinase activity GO:0033133 IEA     fructose 2,6-bisphosphate metabolic process GO:0006003 IEA     glucose metabolic process GO:0006006 TAS     carbohydrate phosphorylation GO:0046835 TAS     small molecule metabolic process GO:0044281 TAS     response to glucose GO:0009749 IEA     canonical glycolysis GO:0061621 TAS Subcellular Localization     cytosol GO:0005829 TAS