Gene description for DTD1
Gene name D-tyrosyl-tRNA deacylase 1
Gene symbol DTD1
Other names/aliases C20orf88
DUE-B
DUEB
HARS2
bA379J5.3
bA555E18.1
pqn-68
Species Homo sapiens
 Database cross references - DTD1
ExoCarta ExoCarta_92675
Vesiclepedia VP_92675
Entrez Gene 92675
HGNC 16219
MIM 610996
UniProt Q8TEA8  
 DTD1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for DTD1
Molecular Function
    tRNA binding GO:0000049 IEA
    DNA binding GO:0003677 EXP
    metal ion binding GO:0046872 IEA
    D-tyrosyl-tRNA(Tyr) deacylase activity GO:0051500 IBA
Biological Process
    DNA replication GO:0006260 IEA
    tRNA metabolic process GO:0006399 IBA
    DNA duplex unwinding GO:0032508 EXP
    aminoacyl-tRNA metabolism involved in translational fidelity GO:0106074 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IBA
    mitochondrion GO:0005739 HTP
 Experiment description of studies that identified DTD1 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for DTD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CAMKV 79012
Affinity Capture-MS Homo sapiens
2 IQCB1  
Affinity Capture-MS Homo sapiens
3 CSNK1E 1454
Co-fractionation Homo sapiens
4 SH2D4A 63898
Co-fractionation Homo sapiens
5 POLK  
Affinity Capture-MS Homo sapiens
6 PLS1 5357
Affinity Capture-MS Homo sapiens
7 NEK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 ANKMY2 57037
Co-fractionation Homo sapiens
9 CYP1A1  
Affinity Capture-MS Homo sapiens
10 MAN2B1 4125
Co-fractionation Homo sapiens
11 HSF1  
Co-fractionation Homo sapiens
12 HARS 3035
Co-fractionation Homo sapiens
13 KLHL24  
Affinity Capture-MS Homo sapiens
14 MSX2  
Affinity Capture-MS Homo sapiens
15 TNNC2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which DTD1 is involved
No pathways found





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