Gene description for KRT71
Gene name keratin 71, type II
Gene symbol KRT71
Other names/aliases HYPT13
K6IRS1
KRT6IRS
KRT6IRS1
Species Homo sapiens
 Database cross references - KRT71
ExoCarta ExoCarta_112802
Entrez Gene 112802
HGNC 28927
MIM 608245
UniProt Q3SY84  
 KRT71 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for KRT71
Molecular Function
    protein binding GO:0005515 IPI
    structural molecule activity GO:0005198 IEA
Biological Process
    intermediate filament organization GO:0045109 IMP
    hair follicle morphogenesis GO:0031069 IMP
Subcellular Localization
    keratin filament GO:0045095 IDA
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified KRT71 in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KRT71
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which KRT71 is involved
No pathways found





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