Experiment description of studies that identified DIRAS2 in sEVs

1 Experiment ID 126 MISEV standards ✘ Biophysical techniques ✔ GAPDH Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry [LTQ-FT Ultra] PubMed ID Unpublished / Not applicable Organism Homo sapiens Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim" Journal name Mesenchymal Stem Cell Therapy Publication year 2011 Sample Mesenchymal stem cells Sample name huES9.E1 Isolation/purification methods HPLC Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Antobody array Mass spectrometry

2 Experiment ID 191 MISEV standards ✘ Biophysical techniques ✔ Alix|CD81|CD9 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20124223     Organism Homo sapiens Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK." Journal name Mol Cell Proteomics Publication year 2010 Sample Squamous carcinoma cells Sample name Squamous carcinoma cell (A431) Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for DIRAS2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HSPA5 3309 Affinity Capture-MS Homo sapiens 2 RAP1GDS1 5910 Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 KRT1 3848 Affinity Capture-MS Homo sapiens 4 HSPA8 3312 Affinity Capture-MS Homo sapiens 5 PKM 5315 Affinity Capture-MS Homo sapiens 6 UNC45A 55898 Two-hybrid Homo sapiens 7 RIPPLY1   Two-hybrid Homo sapiens 8 RLIM 51132 Affinity Capture-MS Homo sapiens 9 HRNR 388697 Affinity Capture-MS Homo sapiens 10 C1orf86   Affinity Capture-MS Homo sapiens 11 TUBB4B 10383 Affinity Capture-MS Homo sapiens 12 HSP90AB1 3326 Affinity Capture-MS Homo sapiens 13 Htt   Affinity Capture-MS Mus musculus 14 PARK2   Affinity Capture-MS Homo sapiens 15 HSP90AA1 3320 Affinity Capture-MS Homo sapiens 16 KRT6A 3853 Affinity Capture-MS Homo sapiens 17 IGKV2-28   Affinity Capture-MS Homo sapiens 18 SIRPD   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 UNC13B 10497 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 DIRAS1 148252 Affinity Capture-MS Homo sapiens 21 PSMD2 5708 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 22 SPOP   Affinity Capture-MS Homo sapiens 23 FTO 79068 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 KRT9 3857 Affinity Capture-MS Homo sapiens 25 KRT10 3858 Affinity Capture-MS Homo sapiens 26 ALYREF 10189 Affinity Capture-MS Homo sapiens 27 KRT2 3849 Affinity Capture-MS Homo sapiens 28 ZNF581   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 29 HSPA9 3313 Affinity Capture-MS Homo sapiens 30 KRT16 3868 Affinity Capture-MS Homo sapiens 31 ATP5B 506 Affinity Capture-MS Homo sapiens View the network

Pathways in which DIRAS2 is involved

No pathways found