Experiment description of studies that identified CLIP2 in exosomes

1 Experiment ID 237 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH EV Cytosolic markers ✘ EV Membrane markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

2 Experiment ID 52 ISEV standards ✔ EM EV Biophysical techniques ✔ HSP90 EV Cytosolic markers ✔ MHCII EV Membrane markers ✘ EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 14975938     Organism Homo sapiens Experiment description Proteomic analysis of exosomes isolated from human malignant pleural effusions. Authors Bard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen LA, van Meerbeeck JP, Burgers SA, Hoogsteden HC, Lambrecht BN Journal name AJRCMB Publication year 2004 Sample Malignant pleural effusions Sample name Pleural Fluid - Lung cancer Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [MALDI TOF] Western blotting

3 Experiment ID 53 ISEV standards ✔ EM EV Biophysical techniques ✔ HSP90 EV Cytosolic markers ✔ MHCII EV Membrane markers ✘ EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 14975938     Organism Homo sapiens Experiment description Proteomic analysis of exosomes isolated from human malignant pleural effusions. Authors Bard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen LA, van Meerbeeck JP, Burgers SA, Hoogsteden HC, Lambrecht BN Journal name AJRCMB Publication year 2004 Sample Malignant pleural effusions Sample name Pleural Fluid - Mesothelioma Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [MALDI TOF] Western blotting

Protein-protein interactions for CLIP2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CLASP2 23122 Reconstituted Complex Homo sapiens 2 CLASP1 23332 Reconstituted Complex Homo sapiens View the network

Pathways in which CLIP2 is involved

No pathways found