Gene description for TRPV4
Gene name	transient receptor potential cation channel, subfamily V, member 4
Gene symbol	TRPV4
Other names/aliases	BCYM3 CMT2C HMSN2C OTRPC4 SMAL SPSMA SSQTL1 TRP12 VRL2 VROAC
Species	Homo sapiens
Database cross references - TRPV4
ExoCarta	ExoCarta_59341
Vesiclepedia	VP_59341
Entrez Gene	59341
HGNC	18083
MIM	605427
UniProt	Q9HBA0
TRPV4 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for TRPV4

Molecular Function     SH2 domain binding GO:0042169 ISS     actin filament binding GO:0051015 ISS     calmodulin binding GO:0005516 IMP     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     osmosensor activity GO:0005034 IEA     beta-tubulin binding GO:0048487 ISS     microtubule binding GO:0008017 ISS     alpha-tubulin binding GO:0043014 ISS     calcium channel activity GO:0005262 IDA     protein kinase C binding GO:0005080 ISS     cation channel activity GO:0005261 IDA     protein kinase binding GO:0019901 IPI     actin binding GO:0003779 ISS Biological Process     positive regulation of cytosolic calcium ion concentration GO:0007204 IDA     vasopressin secretion GO:0030103 IEA     cellular calcium ion homeostasis GO:0006874 IDA     calcium ion transmembrane transport GO:0070588 TAS     cortical microtubule organization GO:0043622 ISS     cell-cell junction assembly GO:0007043 ISS     response to mechanical stimulus GO:0009612 TAS     cellular hypotonic response GO:0071476 ISS     hyperosmotic salinity response GO:0042538 IEA     transmembrane transport GO:0055085 TAS     cellular response to heat GO:0034605 ISS     negative regulation of neuron projection development GO:0010977 ISS     cell volume homeostasis GO:0006884 TAS     ion transmembrane transport GO:0034220 TAS     microtubule polymerization GO:0046785 ISS     calcium ion import GO:0070509 ISS     calcium ion transport GO:0006816 NAS     regulation of response to osmotic stress GO:0047484 IEA     actin filament organization GO:0007015 ISS     osmosensory signaling pathway GO:0007231 TAS     positive regulation of microtubule depolymerization GO:0031117 ISS     actin cytoskeleton reorganization GO:0031532 ISS     cellular response to osmotic stress GO:0071470 ISS Subcellular Localization     adherens junction GO:0005912 ISS     cytosol GO:0005829 IEA     cytoplasmic microtubule GO:0005881 ISS     growth cone GO:0030426 ISS     plasma membrane GO:0005886 TAS     filopodium GO:0030175 ISS     cortical actin cytoskeleton GO:0030864 ISS     cell surface GO:0009986 IEA     ruffle membrane GO:0032587 ISS     cytoplasmic vesicle GO:0031410 IEA     integral component of membrane GO:0016021 NAS     lamellipodium GO:0030027 ISS     focal adhesion GO:0005925 ISS     cilium GO:0005929 IEA